1st EuroTauMeetingÉvénementColloque

1st EuroTauMeeting

BiologieChimie
ChercheurDoctorant
Pôle événementiel
27/04/2017 - 08:30 - 28/04/2017 - 16:00

European scientists involved in Tau research will gather at LILLIAD Learning center Innovation in Lille, to exchange new ideas and hypotheses on physiological and pathological roles of tau proteins.

Registration is free but required. You have until April 10, 2017 to contact laetitia.coudert@univ-lille2.fr.

Confirmed speakers

  • Irina Alafuzoff, J Gobom & K Höglund, Sweden
  • Johannes Attems, UK
  • Jesus Avila & Miguel Medina, Spain
  • Dirk Beher & Amy Pooler, Switzerland
  • David Blum, Morvane Colin, France
  • Jean-Pierre Brion, ULB, Belgium
  • Vincent Deramecourt & Thibaud Lebouvier
  • Bart Dermaut & Marie Galas, France
  • Michel Goedert & Diane Hanger, UK
  • Isabelle Landrieu & Malika Hamdane, France
  • Günter Höglinger, Germany
  • Illana Gozes, Israel
  • Eva Maria & Eckhard Mandelkow, Germany
  • Maï Panchal, LECMA, France & Rosa Sancho, ARUK, UK
  • Alberto Rabano & Laura Sayas, Spain
  • Melita Salkovic, Croatia
  • Wiep Scheper, The Netherlands
  • Efthimios Skoulakis, Greece
  • Ioannis Sotiropoulos, Portugal
  • Amrit Mudher, Maria Grazia Spillantini & Selina Wray, UK
  • Norbert Zilka, Tomas Smolek, Michal Novak, Slovakia

Program

April 27, 2017

8:30

Welcome participants

9:30

Welcome address (Luc Buée and Univ. Lille representatives)

10:00 — 12:00

Session 1

  • 10:00 — 10:15  - Irina Alafuzoff, Sweden: Tau pathology (incidence and distribution) in humans in various ages and clinical conditions
  • 10:15 - 10:30  - Johannes Attems, UK: The role of tau in the multi-morbid old brain
  • 10:30 — 10:45  — Alberto Rabano, Spain: Tau immunoreactive nuclear indentations in the entorhinal cortex of early Alzheimer’s pathology
  • 10:45 - 11:00  - Michel Goedert, UK: The atomic structures of Tau filaments from Alzheimer’s disease brain
  • 11:00 — 11:15 — Günter Höglinger, Germany: PSP and CBD: human tauopathy model diseases
  • 11:15 — 11:30 — Maria Grazia Spillantini, UK: Neurons and glia interaction in tauopathies
  • 11:30 — 11:45 — Eckhard Mandelkow, Germany: Structural aspects of Tau
  • 11:45 — 12:00 — Isabelle Landrieu, France: Characterization of Tau interactions using NMR spectroscopy

 

12:00 — 13:30

Lunch and Poster session

13:30 — 15 :00

Session 2

  • 13:30 — 13:45 — Jesus Avila, Spain: Influence of tau levels and phosphorylation in cognition
  • 13:45 — 14:00 — Malika Hamdane, France: Amino-truncated Tau species
  • 14:00 — 14:15 — Laura Sayas, Spain: Interplay between tau and End binding proteins in neuronal cells
  • 14:15 - 14:30 — Marie Galas, France: Nuclear Tau regulates the structure of neuronal pericentromeric heterochromatin
  • 14:30-14:45 - Efthimios Skoulakis, Greece: Tau as a metalloprotein
  • 14:45 — 15:00 — David Blum, France: Tau: a new regulator of brain insulin signaling
  • 15:15 — 15:30 — Thibaud Lebouvier, France: Clinical and neuropathological aspects of Tauopathies
  • 15:30 - 15:45 - Anne Rovelet-Lecrux, France: MAPT locus and microduplication

15:45 — 16:15

Coffee break

16:15 — 17:00

Session 3

  • 16:15 — 16:30 — Bart Dermaut, France: A developmental role for Tau in adult-onset neurodegenerative disease?
  • 16:30 — 16:45 — Amrit Mudher, UK: One protein, 6 isoforms, numerous functions: isoform-specific tau-toxicity
  • 16:45 - 17:00 - Miguel Medina, Spain: Tau secretion and toxicity
  • 17:00 — 17:15 — Morvane Colin, France: Tau intercellular transfer: from TNTs to extracellular vesicles
  • 17:15 — 17:30 — Eva Maria Mandelkow, Germany: Animal models of Tauopathy
  • 17:30 — 17:45 — Jean-Pierre Brion, Belgium: Tau pathology propagation in in vivo models induced by native human Alzheimer PHF

April 28, 2017

8:30 — 10:30

Session 4

  • 8:30 — 8:45 — Melita Salkovic, Croatia: Pathology of tau protein in a non-transgenic rat model of sporadic Alzheimer’s disease
  • 8:45 - 9:00 - Ioannis Sotiropoulos, Portugal: role of Tau on stress-related brain pathologies
  • 9:00 — 9:15 — Illana Gozes, Israel: ADNP: indirect interactions with tau determine cellular faith
  • 9:15 — 9:30 — Wiep Scheper, The Netherlands: UPR and tau pathology
  • 9:30 — 9:45 — Johan Gobom, Sweden: Overview of tau biomarkers in CSF and blood
  • 9:45 — 10:00 — Selina Wray, UK: Human stem cell derived neurons as models of tauopathy
  • 10:00 — 10:15 — Norbert Zilka, Tomas Smolek, Michal Novak, Slovakia: The driver and the others: Monitoring of human AD tau spreading in vivo
  • 10:15 - 10:30 - Dirk Beher, Switzerland: O-GlcNAcase inhibitors for tauopathies – translation of a research finding to a clinical candidate molecule

10:30 — 11:00

Coffee break

11:00 — 12:00

Parallel sessions of round tables (biomarkers, therapeutics, experimental models, ect.)

12:00 — 13:45

Round tables conclusions

12:45 — 14:00

Lunch & Poster session

14:00 — 14:30

Funding Opportunities

  • 14:00 — 14:15 — Rosa Sancho, ARUK, UK: Funding opportunities
  • 14:15 — 14:30 — Maï Panchal, LECMA, France: Presentation of LECMA-Vaincre Alzheimer and its European network of non-profit organizations

14:30 — 15:15

Flash-talks of selected posters

  • 14:30 — 14:35 — Flash-talks presentation
  • 14:35 — 14:45 — Selected poster 1
  • 14:45 — 14:55 — Selected poster 2
  • 14:55 — 15:05 — Selected poster 3
  • 15:05 — 15:15 — Awards

15:15 — 16:00

Informal discussion

16:00

Closing of the meeting

More information on the meeting (scientific committee, posters, ect.) on their website.

Go further

A short video explaining th how and the why of Alzheimer disease, directed by the LECMA association:

Another short scientific popularization video (in French, English subtitles available) about Tau protein:

Consulter la bibliographie Lilliad